As expected, the most recent study linking GE corn to cancer in rates has stirred up a storm from the right wing media. There are usually two strategies that the right wing media tries. The first is to query the methodology of the study (forgetting in this case that it was published in the same peer reviewed journal as Monsantos original study – on which approval of the corn variety was based). If questioning the methodology doesnt work, the next strategy is questioning the integrity of the scientists. In the case of the Seralini study, what is interesting is the virulent nature of the comments coming in, such as opinion piece in the National Post yesterday (which I am not going to post here but you can find for yourselves). Biotech seems to be on the run in this case! But what is clear from the Seralini study is that we dont know if GE crops are safe or not, and if theres any doubt, they shouldnt be on the market.
The piece below, signed by a number of scientists, details the history of attacks on scientists who have carried out independent research on GE crops.
Seralini and Science: an Open Letter
Posted By jrlatham On October 2, 2012 @ 12:19 am In Biotechnology,Commentaries,Health Independent Science News http://independentsciencenews.org/health/seralini-and-science-nk603-rat-study-roundup/print/
(Authors listed below)
A new paper by the French group of Gilles-Eric Seralini describes harmful effects on rats fed diets containing genetically modified maize (variety NK603), with and without the herbicide Roundup, as well as Roundup alone. This peer-reviewed study (Seralini et al., 2012 ), has been criticized by some scientists whose views have been widely reported in the popular press (Carmen, 2012; Mestel, 2012; Revkin, 2012; Worstall, 2012). Seralini et al. (2012) extends the work of other studies demonstrating toxicity and/or endocrine-based impacts of Roundup (Gaivão et al., 2012; Kelly et al., 2010; Paganelli et al., 2010; Romano et al., 2012), as reviewed by Antoniou et al. (2010).
The Seralini publication, and resultant media attention, raise the profile of fundamental challenges faced by science in a world increasingly dominated by corporate influence. These challenges are important for all of science but are rarely discussed in scientific venues. 
1) History of Attacks on Risk-finding Studies. Seralini and colleagues are just the latest in a series of researchers whose findings have triggered orchestrated campaigns of harassment. Examples from just the last few years include Ignacio Chapela, a then untenured Assistant Professor at Berkeley, whose paper on GM contamination of maize in Mexico (Quist and Chapela, 2001) sparked an intensive internet-based campaign to discredit him. This campaign was reportedly masterminded by the Bivings Group, a public relations firm specializing in viral marketing – and frequently hired by Monsanto (Delborne, 2008).
The distinguished career of biochemist Arpad Pusztai, came to an effective end when he attempted to report his contradictory findings on GM potatoes (Ewen and Pusztai, 1999a). Everything from a gag order, forced retirement, seizure of data, and harassment by the British Royal Society were used to forestall his continued research (Ewen and Pusztai, 1999b; Laidlaw, 2003). Even threats of physical violence have been used, most recently against Andres Carrasco, Professor of Molecular Embryology at the University of Buenos Aires, whose research (Paganelli et al. 2010) identified health risks from glyphosate, the active ingredient in Roundup (Amnesty International, 2010).
It was no surprise therefore, that when in 2009, 26 corn entomologists took the unprecedented step of writing directly to the US EPA to complain about industry control of access to GM crops for research, the letter was sent anonymously (Pollack, 2009).
2) The Role of the Science Media. An important but often unnoticed aspect of this intimidation is that it frequently occurs in concert with the science media (Ermakova, 2007; Heinemann and Traavik, 2007; Latham and Wilson, 2007). Reporting of the Seralini paper in arguably the most prestigious segments of the science media: Science, the New York Times, New Scientist, and the Washington Post uniformly failed to “balance” criticism of the research, with even minimal coverage of support for the Seralini paper (Carmen, 2012; Enserink, 2012; MacKenzie, 2012; Pollack, 2012). Nevertheless, less well-resourced media outlets, such as the UK Daily Mail appeared to have no trouble finding a positive scientific opinion on the same study (Poulter, 2012).
3) Misleading Media Reporting. A key pattern with risk-finding studies is that the criticisms voiced in the media are often red herrings, misleading, or untruthful. Thus, the use of common methodologies was portrayed as indicative of shoddy science when used by Seralini et al. (2012) but not when used by industry (see refs above and Science Media Centre, 2012). The use of red herring arguments appears intended to sow doubt and confusion among non-experts. For example, Tom Sanders of Kings College, London was quoted as saying: “This strain of rat is very prone to mammary tumors particularly when food intake is not restricted” (Hirschler and Kelland, 2012 ). He failed to point out, or was unaware, that most industry feeding studies have used Sprague-Dawley rats (e.g. Hammond et al., 1996, 2004, 2006; MacKenzie et al., 2007). In these and other industry studies (e.g. Malley et al. 2007), feed intake was unrestricted. Sanders’ comments are important because they were widely quoted and because they were part of an orchestrated response to the Seralini study by the Science Media Centre of the British Royal Institution. The Science Media Centre has a long history of quelling GMO controversies and its funders include numerous companies that produce GMOs and pesticides.
4) Regulator Culpability. In our view a large part of the ultimate fault for this controversy lies with regulators. Regulators, such as EFSA (the European Food Safety Authority) in Europe and the EPA (Environmental Protection Agency) and FDA (Food and Drug Administration) in the US, have enshrined protocols with little or no potential to detect adverse consequences of GMOs (Schubert, 2002; Freese and Schubert, 2004; Pelletier, 2005).
GMOs are required to undergo few experiments, few endpoints are examined, and tests are solely conducted by the applicant or their agents. Moreover, current regulatory protocols are simplistic and assumptions-based (RSC, 2001), which by design, will miss most gene expression changes – apart from the target trait – induced by the process of transgene insertion (Heinemann et al., 2011; Schubert, 2002).
Puzstai (2001) and others have consequently argued that well-conducted feeding trials are one of the best ways of detecting such unpredictable changes. Yet feeding trials are not mandatory for regulatory approval, and the scientific credibility of those which have been published to date has been challenged (Domingo, 2007; Pusztai et al., 2003; Spiroux de Vendômois et al., 2009). For example, Snell et al. (2012), who assessed the quality of 12 long term (>96 days) and 12 multigenerational studies, concluded: “The studies reviewed here are often linked to an inadequate experimental design that has detrimental effects on statistical analysis…the major insufficiencies not only include lack of use of near isogenic lines but also statistical power underestimation [and], absence of repetitions…”.
Apparently, the same issues of experimental design and analysis raised about this (Seralini) risk-finding study were not of concern to critics when the studies did not identify risk, resulting in ill-informed decision-makers. In the end, it is a major problem for science and society when current regulatory protocols approve GMO crops based on little to no useful data upon which to assess safety.
5) Science and Politics. Governments have become habituated to using science as a political football. For example, in a study conducted by the Royal Society of Canada at the request of the Canadian government, numerous weaknesses of GM regulation in Canada were identified (RSC, 2001). The failure of the Canadian government to meaningfully respond to the many recommended changes was detailed by Andree (2006). Similarly, the expert recommendations of the international IAASTD  report, produced by 400 researchers over 6 years, that GMOs are unsuited to the task of advancing global agriculture have been resolutely ignored by policymakers. Thus, while proclaiming evidence-based decision-making, governments frequently use science solely when it suits them.
6) Conclusion: When those with a vested interest attempt to sow unreasonable doubt around inconvenient results, or when governments exploit political opportunities by picking and choosing from scientific evidence, they jeopardize public confidence in scientific methods and institutions, and also put their own citizenry at risk. Safety testing, science-based regulation, and the scientific process itself, depend crucially on widespread trust in a body of scientists devoted to the public interest and professional integrity. If instead, the starting point of a scientific product assessment is an approval process rigged in favour of the applicant, backed up by systematic suppression of independent scientists working in the public interest, then there can never be an honest, rational or scientific debate.
The Authors: Susan Bardocz (4, Arato Street, Budapest, 1121 Hungary); Ann Clark (University of Guelph, ret.); Stanley Ewen (Consultant Histopathologist, Grampian University Hospital); Michael Hansen (Consumers Union); Jack Heinemann (University of Canterbury); (Jonathan Latham (The Bioscience Resource Project); Arpad Pusztai (4, Arato Street, Budapest, 1121 Hungary); David Schubert (The Salk Institute); Allison Wilson (The Bioscience Resource Project)
Signatories: Brian Wynne (Professor of Science Studies, UK Economic and Social Research Council (ESRC) Centre for Economic and Social Aspects of Genomics, Cesagen, Lancaster University); Irina Ermakova, Dr of biology, Russian Academy of Sciences; Jo Cummins (professor emeritus university of western Ontario); Michael Antoniou, (Reader in Molecular Genetics, London); Philip L. Bereano (Professor Emeritus University of Washington & Washington Biotechnology Action Council); Dr P M Bhargava (Former and Founder Director, Centre for Cellular & Molecular Biology, Government of India); Carlo Leifert (Professor for Ecological Agriculture Newcastle University); Peter Romilly (formerly University of Abertay, Dundee); Robert Vint (FRSA); Dr Brian John (Durham University, UK, retired); Professor C. Vyvyan Howard, University of Ulster); Diederick Sprangers (Genethics Foundation); Mariam Mayet (African Centre for Biosafety, South Africa).
and if you would like your name added to this list, please email: isneditor (at) bioscienceresource.org and write ‘Seralini letter’ in the headline, providing an affiliation if you wish.
(1) In addition, US scientists who publish studies finding adverse environmental effects are frequently vehemently attacked by other pro-GM scientists. As a report in Nature, which discusses numerous examples, points out, “Papers suggesting that biotech crops might harm the environment attract a hail of abuse from other scientists. Behind the attacks are scientists who are determined to prevent papers they deem to have scientific flaws from influencing policy-makers. When a paper comes out in which they see problems, they react quickly, criticize the work in public forums, write rebuttal letters, and send them to policy-makers, funding agencies and journal editors” (pg. 27 in Waltz. 2009a . Indeed, when one of us wrote a Commentary in Nature Biotechnology ten years ago suggesting that more attention needs to be paid to the potential unintended effects associated with insertional mutagenesis, we received a flood of responses, and an administrator at the Salk Institute even said that the publication “was jeopardizing funding for his institution” (see Waltz, 2009a). Similar attacks have greeted studies on adverse effects of Bt toxins on ladybird beetles and green lacewing larvae, which were used by German authorities to ban cultivation of Mon810, a Bt corn variety (see: Hilbeck et al. 2012a,b , respectively). In 2009, a group of 26 public sector corn entomologists sent a letter to the US Environmental Protection Agency which stated “No truly independent research can be legally conducted on many critical questions involving these crops [because of company-imposed restrictions]” (pg. 880 in Waltz, 2009b ; it was no surprise that the letter was sent anonymously as the scientists feared retribution from the companies that funded their work (Pollack, 2009). Furthermore, industry control over what research can be conducted in the US means that adverse findings can effectively be suppressed. In one example cited in the article, Pioneer was developing a binary Bt toxin, Cry34Ab1/Cry35Ab1, against the corn rootworm. In 2001, Pioneer contracted with some university laboratories to test for unintended effects on a lady beetle. The laboratories found that 100% of the lady beetles died after eight days of feeding. Pioneer forbade the researchers from publicizing the data. Two years later Pioneer received approval for a Bt corn variety with Cry34Ab1/Cry35Ab1 and submitted studies showing that lady beetles fed the toxin for only 7 days were not harmed. The scientists were not allowed to redo the study after the crop was commercialized (Waltz, 2009b). In another example, Dow AgroSciences threatened a researcher with legal action if he published information he had received from US EPA. As the article notes, “The information concerned an insect-resistant variety of maize known as TC1507, made by Dow and Pioneer. The companies suspended sales of TC1507 in Puerto Rico after discovering in 2006 that an armyworm had developed resistance to it. Tabashnik was able to review the report the companies filed with the EPA by submitting a Freedom of Information Act request. “I encouraged an employee of the company [Dow] to publish the data and mentioned that, alternatively, I could cite the data,” says Tabashnik. “He told me that if I cited the information…I would be subject to legal action by the company,” he says. “These kinds of statements are chilling” (pg. 882 in Waltz, 2009b).
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Article printed from Independent Science News | Food, Health and Agriculture Bioscience News: http://independentsciencenews.org
URLs in this post:
 Seralini et al., 2012: http://dx.doi.org/10.1016/j.fct.2012.08.005
 Image: http://independentsciencenews.org/health/seralini-and-science-nk603-rat-study-roundup/attachment/gilles-eric-seralini/
 IAASTD: http://independentsciencenews.org/environment/science-media-failed-the-iaastd/
 Waltz. 2009a: http://www.nature.com/news/2009/090902/pdf/461027a.pdf
 Waltz, 2009b: http://www.emilywaltz.com/Biotech_crop_research_restrictions_Oct_2009.pdf
 Argentina: Threats deny community access to research:http://www.amnesty.org/en/library/asset/AMR13/005/2010/en/303e9ee6-9138-405f-97fc-ed58965b76d0/amr130052010en.html
 GM Soy: Sustainable? Responsible?: http://www.gmwatch.eu/images/pdf/gm_full_eng_v15.pdf
 French scientists question safety of GM corn: http://www.washingtonpost.com/blogs/all-we-can-eat/post/french-scientists-question-safety-of-gm-corn/2012/09/19/d2ed52e4-027c-11e2-8102-ebee9c66e190_blog.html
 France and European Commission order review of controversial GM study in rats:http://news.sciencemag.org/scienceinsider/2012/09/france-and-european-commission-o.html
 GM soybeans: revisiting a controversial format: http://web.ebscohost.com.subzero.lib.uoguelph.ca/ehost/pdfviewer/pdfviewer?vid=3&hid=123&sid=3246c11d-686f-4de8-a9b0-7e7872af68fd%40sessionmgr115
 Health risks of genetically modified foods.: http://www.lancet.com/journals/lancet/article/PIIS0140-6736%2805%2977668-6/fulltext” http://www.lancet.com/journals/lancet/article/PIIS0140-6736%2805%2977668-6/fulltext
 Safety Testing and Regulation of Genetically Engineered Food: http://www.google.com/url?sa=t&rct=j&q=safety%20testing%20and%20regulation%20of%20genetically%20engineered%20food&source=web&cd=1&cad=rja&ved=0CCcQFjAA&url=http%3A%2F%2Fwww.saveourseeds.org%2Fdownloads%2Fschubert_safety_reg_us_11_2004.pdf&ei=geJpUJn_HvLG0AHJr4CYDA&usg=AFQjCNFuSRycBJK0OAOFUnSStAv1IhvfxA
 Underlying reasons of the controversy over adverse effects of Bt toxins on lady beetle and lacewing larvae.:http://www.enveurope.com/content/pdf/2190-4715-24-9.pdf
 Study on Monsanto GM corn concerns draws skepticism: http://uk.reuters.com/article/2012/09/20/us-gmcrops-safety-idUKBRE88J0MS20120920
 What is Nature Biotechnology good for?: http://independentsciencenews.org/health/nature-biotechnology/
 Study linking GM crops and cancer questioned: http://www.newscientist.com/article/dn22287-study-linking-gm-crops-and-cancer-questioned.html
 Study points to health problems with genetically modified foods: http://www.latimes.com/news/science/la-sci-gmo-food-study-20120920,0,3467735.story
 Crop scientists say biotechnology seed companies are thwarting research:http://www.nytimes.com/2009/02/20/business/20crop.html
 Foes of modified corn find support in a study: http://www.nytimes.com/2012/09/20/business/energy-environment/disputed-study-links-modified-corn-to-greater-health-risks.html?_r=0refshttp
 Cancer row over GM foods as study says it did THIS to rats… and can cause organ damage and early death in humans:http://www.dailymail.co.uk/sciencetech/article-2205509/Cancer-row-GM-foods-French-study-claims-did-THIS-rats–cause-organ-damage-early-death-humans.html
 Genetically Modified Foods: Are They a Risk to Human/Animal Health?: http://www.actionbioscience.org/biotech/pusztai.html
 Single-Study Syndrome and the G.M.O. Fight.: http://dotearth.blogs.nytimes.com/2012/09/20/the-gmo-food-fight-rats-cancer-and-single-study-syndrome/
 Elements of Precaution: Recommendations for the Regulation of Food Biotechnology In Canada:http://www.rsc.ca/files/publications/expert_panels/foodbiotechnology/GMreportEN.pdf
 Study on cancer and GM maize – experts respond: http://www.sciencemediacentre.co.nz/2012/09/20/study-on-cancer-and-gm-maize-experts-respond/
 Proof Perfect That The Seralini Paper On GM Corn And Cancer In Rats Is Rubbish:http://www.forbes.com/sites/timworstall/2012/09/21/proof-perfect-that-the-seralini-paper-on-gm-corn-and-cancer-in-rats-is-rubbish/